Intellectual disability is common. Half of children with this syndrome learn enough verbal skills to communicate. The cat-like cry becomes less noticeable over time.
Complications depend on the amount of intellectual disability and physical problems. Symptoms may affect the person's ability to care for themselves.
When to Contact a Medical Professional
This syndrome is usually diagnosed at birth. Your health care provider will discuss your baby's symptoms with you. It is important to continue regular visits with the child's health care providers after leaving the hospital.
Genetic counseling and testing is recommended for all persons with a family history of this syndrome.
There is no known prevention. Couples with a family history of this syndrome who wish to become pregnant may consider genetic counseling.
Bacino CA, Lee B. Cytogenetics. In: Kliegman RM, Stanton BF, St. Geme JW III, Shor NF, Behrman RE, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 76.
Chad Haldeman-Englert, MD, FACMG, Wake Forest School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.