The hormone prolactin is a little high in a small percentage of patients. This may interfere with the normal function of the testicles or ovaries.
For primary empty sella syndrome:
There is no treatment if pituitary function is normal.
Medications such as bromocriptine, which lower prolactin levels, may be prescribed if prolactin levels are high and interfering with the function of the ovaries or testes.
For secondary empty sella syndrome:
Treatment involves replacing the hormones that are lacking.
Primary empty sella syndrome does not cause health problems, and it does not affect life expectancy.
Complications of primary empty sella syndrome include mild hyperprolactinemia.
Complications of secondary empty sella syndrome are related to the cause of pituitary gland disease or to the effects of too little pituitary hormone.
Calling your health care provider
Contact your health care provider if you develop symptoms of abnormal pituitary function, such as a disrupted menstrual cycle or impotence.
Melmed S, Kleinberg D, Ho Ken. Pituitary physiology and diagnostic evaluation. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 12th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 8.
Ari S. Eckman, MD, Division of Endocrinology and Nancy J. Rennert, MD, Chief of Endocrinology & Diabetes, Norwalk Hospital, Associate Clinical Professor of Medicine, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.