Surgery to remove the tumor is the preferred treatment. The tumor does not usually respond to chemotherapy.
Approximately 60% of these tumors are cancerous. It is common for this cancer to spread to the liver. Only about 20% of people can be cured with surgery.
If the tumor is only in the pancreas and surgery to remove it is successful, patients have a 5-year survival rate of 85%.
The cancer can spread to the liver. High blood sugar level can cause metabolic problems and tissue damage.
Calling your health care provider
Call your health care provider if you notice symptoms of glucagonoma.
Jensen RT, Norton JA. Endocrine tumors of the pancreas and gastrointestinal tract. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2010:chap 32.
National Cancer Institute: PDQ Pancreatic neuroendocrine tumors (islet cell tumors) treatment. Bethesda, MD: National Cancer Institute. Date last modified 11/10/2012. Available at: http://www.cancer.gov/cancertopics/pdq/treatment/gastric/HealthProfessional. Accessed November 16, 2012.
Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.